Product ID:HYDROQUINONE TABLETS, DIOGNOSTICS CHEMICAL, HT1014
MSDS Date:07/03/2000
FSC:NIIN:Submitter:N EN
Status Code:A
MSDS Number: CKSXW

Emergency Phone: 414-273-3850 EXT 5996

Info Phone: 314-771-5765

Cage: TO571

Telephone: 314-771-5765

Cage: TO571

C6H6O2)

CAS: 123-31-9

RTECS: MX3500000

OSHA PEL 2 MG/M3

ACGIH TLV: 2 MG/M3

EPA Report Quantity: 1 LB

DOT Report Quantity: 1 LB

LD50 LC50 Mixture:LD 50: 320 MG/KG (ORAL, RAT)
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:SKIN CONTACT: CAUSES SEVERE SKIN
IRRITATION. SKIN ABSORPTION: MAY BE HARMFUL IF ABSORBED THROUGH
SKIN. EYE CONTACT: CAUSES EYE IRRITATION. INHALATION: MATERIAL IS
IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT.
HARMFUL IF INHALED. INGESTION: HARMFUL IF INGESTED.
SENSITIZATION: MAY CAUSE ALLERGIC REACTION. TARGET ORGAN(S) OR
SYSTEM(S): KIDNEYS, EYES. SIGNS AND SYMPTOMS OF EXPOSUR E:
PROLONGED EXPOSURE CAN CAUSE: DAMAGE TO THE EYES. TO THE BEST OF
OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL PROPERTIES
HAVE NOT BEEN THOROUGHLY INVESTIGATED. EMERGENCY OVERVIEW: HARM
FUL BY (SIGNS & SYMPTOMS OF OVEREXP)
Explanation of Carcinogenicity:THIS PRODUCT IS OR CONTAINS A COMPONENT
THAT HAS BEEN REPORTED TO BE POSSIBLE CARCINOGENIC BASED ON ITS
IARC, ACGIH, NTP OR EPA CLASSIFICATION. IARC CARCINOGEN LIST:
RATING - GROUP 3. NTP CARCINOGEN LIST: RATING - SOME EVIDENCE,
SPECIES - MOUSE/RAT, ROUTE - GAVAGE. ACGIH CARCINOGEN LIST: RATING
- A3.
Effects of Overexposure:HEALTH HAZARDS ACUTE & CHRONIC (CONT):
INHALATION AND IF SWALLOWED. IRRITATING TO EYES AND RESPIRATORY
SYSTEM. MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT.
POSSIBLE RISK OF IRREVERSIBLE EFF ECTS. POSSIBLE CARCINOGEN (US).
SEVERE SKIN IRRITANT. TARGET ORGAN(S): KIDNEYS, EYES.

First Aid:ORAL EXPOSURE: IF SWALLOWED, WASH OUT MOUTH WITH WATER
PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN. INHALATION
EXPOSURE: IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE
ARTIFICIAL RESPIRATI ON. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
DERMAL EXPOSURE: IN CASE OF SKIN CONTACT, FLUSH WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. REMOVE CONTAMINATED
CLOTHING AND SHOES. CALL A PHYSI CIAN. EYE EXPOSURE: IN CASE OF
CONTACT WITH EYES, FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST
15 MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING THE EYELIDS WITH
FINGERS. CALL A PHYSICIAN.

Autoignition Temp:=499.C, 930.2F
Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER,
OR APPROPRIATE FOAM.
Fire Fighting Procedures:WEAR (NIOSH APPROVED - ) SELF-CONTAINED
BREATHING APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH
SKIN AND EYES.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR
SPILL: EVACUATE AREA. PROCEDURE(S) FO PERSONAL PRECAUTION(S): WEAR
RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS, AND HEAVY RUBBER
GLOVES. METHODS FOR CLEANING UP: SWEEP UP, PLACE IN A BAG AND
HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE AREA AND
WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:HANDLING, USER EXPOSURE: DO NOT
BREATHE DUST. AVOID CONTACT WITH EYES, SKIN AND CLOTHING. AVOID
PROLONGED OR REPEATED EXPOSURE. STORAGE, SUITABLE: STORE IN A COOL
DRY PLACE. KEEP TIGHTLY CLOSED.

Respiratory Protection:NIOSH-APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:COMPATIBLE CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL SAFETY GOGGLES AND FULL
FACESHIELD .
Other Protective Equipment:SAFETY SHOWER AND EYE BATH (MEETING ANSI
DESIGN CRITERIA - ).
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
PHYSICAL / CHEMICAL PROPERTIES (CONT): MOLECULAR WEIGHT: 110.11 AMU.
SATURATED VAPOR CONC.: N/A. BULK DENSITY: N/A. ODOR THRESHOLD:
N/A. VOC CONTENT: N/A. WATER CONTENT: N/A. SOLVENT CONTENT: N/
A. PARTITION COEFFICIENT: N/A. DECOMPOSITION TEMP.: N/A.

Boiling Pt:=285.C, 545.F
B.P. Text:@ 760 MM HG
Melt/Freeze Pt:=171.C, 339.8F
Vapor Pres:1 MM HG @ 132 C
Vapor Density:3.81 G/L
Solubility in Water:50 MG/ML H2O, CLEAR
Appearance and Odor:FINE CRYSTALS, COLORLESS

Stability Indicator/Materials to Avoid:YES
STRONG BASES, STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:AIR SENSITIVE.
Hazardous Decomposition Products:CARBON MONOXIDE, CARBON DIOXIDE.
Conditions to Avoid Polymerization:WILL NOT OCCUR.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:EXPOSURE LIMITS, RTECS: (SEE INGREDIENTS
SECTION FOR ADDITIONAL VALUES - FPN). COUNTRY - USA, SOURCS - MSHA
STANDARD AIR, TYPE - TWA, VALUE - 2 MG/M3. COUNTRY - NEW ZEALAND,
SOURCE - OEL, REMARKS - CH ECK ACGIH TLV. COUNTRY - USA, SOURCE -
NIOSH, TYPE - CEILING CONCENTRATION, VALUE - 2 MG/M3/15M. TOXICITY
DATA: ORAL - HUMAN: 29 MG/KG (LDLO). ORAL - RAT: 320 MG/KG (LD50),
REMARKS: BEHAVIORAL: TREMO R, BEHAVIORAL: CONVULSIONS OR EFFECT ON
SEIZURE THRESHOLD, BEHAVIORAL: EXCITEMENT. INTRAPERITONEAL - RAT:
170 MG/KG (LD50). INTRAVENOUS - RAT: 115 MG/KG (LD50), REMARKS:
BEHAVIORAL: TREMOR, BEHAVIORAL : CONVULSIONS OR (ECOLOGICAL INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:N/P. TOXICOLOGICAL INFO (CONT): EFFECT ON SEIZURE
THRESHOLD, BEHAVIORAL: EXCITEMENT. ORAL - MOUSE: 245 MG/KG (LD50).
INTRAPERITONEAL - MOUSE: 100 MG/KG (LD50). SUBCUTANEOUS - MOUSE:
182 MG/KG (LD50). ORAL - DOG: 200 MG/KG (LD50), REMARKS:
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD, BEHAVIORAL:
EXCITEMENT, GASTROINTESTINAL: NAUSEA OR VOMITING. ORAL - CAT: 70
MG/KG (LD50), REMARKS: BEHA VIORAL: CONVULSIONS OR EFFECT ON
SEIZURE THRESHOLD, BEHAVIORAL: EXCITEMENT, GASTROINTESTINAL:
CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS. ORAL - RABBIT:
200 MG/KG (LD50). INTRAPERITONEAL - RA BBIT: 125 MG/KG
(LD50).(TRANSPORT INFO)

Transport Information:DOT: PROPER SHIPPING NAME: HYDROQUINONE. UN#:
2662. CLASS: 6.1. PACKING GROUP: PACKING GROUP III. PIH: NOT PIH.
IATA: PROPER SHIPPING NAME: HYDROQUINONE. IATA NUMBER: 2662. HAZARD
CLASS: 6.1. PACKING GROUP: III. ECOLOGICAL INFO (CONT): ORAL -
GUINEA PIG: 550 MG/KG (LD50), REMARKS: BEHAVIORAL: TREMOR,
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD, BEHAVIORAL:
EXCITEMENT. ORAL - PIGEON: 300 MG/KG (LD50), REMARKS: BEHAVIORAL:
CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD, BEHAVIORAL: EXCITEMENT,
GASTROINTESTINAL: NAUSEA OR VOMITING. ORAL - MAMMAL: 480 MG/KG
(LD50), REMARKS: BEHAVIORAL: C HANGE IN MOTOR ACTIVITY (STATE REGS)

SARA Title III Information:SARA 313 LISTED: YES. DEMINIMIS: 1%.
NOTES: THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING
REQUIREMENTS. FEDERAL REGS (CONT): HANDLING AND STORAGE: STORE
UNDER NITROGEN. EU DIRECTIVES CLAS SIFICATION: SYMBOL OF DANGER:
XN. INDICATION OF DANGER: HARMFUL. GISK STATEMENTS: R 20/22,
HARMFUL BY INHALATION AND IF SWALLOWED. SAFETY STATEMENTS: S 24/25
39, AVOID CONTACT WITH SKIN AND EYES; WEAR EYE/FACE PROTECTION.
Federal Regulatory Information:US CLASSIFICATION AND LABEL TEXT:
INDICATION OF DANGER: HARMFUL. RISK STATEMENTS: HARMFUL BY
INHALATION AND IF SWALLOWED; IRRITATING TO EYES AND RESPIRATORY
SYSTEM; MAY CAUSE SENSITIZATION BY INHALATI ON AND SKIN CONTACT;
POSSIBLE RISK OF IRREVERSIBLE EFFECTS. SAFETY STATEMENTS: AVOID
EXPOSURE - OBTAIN SPECIAL INSTRUCTIONS BEFORE USE; IN CASE OF
ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE I MMEDIATELY
(SHOW THE LABEL WHERE POSSIBLE); WEAR SUITABLE PROTECTIVE CLOTHING,
GLOVES, AND EYE/FACE PROTECTION; DO NOT BREATHE DUST. US
STATEMENTS: POSSIBLE CARCINOGEN (US); SEVERE SKIN IRRITANT; TARGET
ORGAN(S): KIDNEYS, EYES. (SARA III)
State Regulatory Information:N/P. TRANSPORTATION INFO (CONT):
(SPECIFIC ASSAY); BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY;
LUNGS, THORAX, OR RESPIRATION: DYSPNEA. SKIN - MAMMAL: 5,970 MG/KG
(LD50). IRRITATION DATA: SKIN - HU MAN: 2%, REMARKS: MILD
IRRITATION EFFECT. SKIN - HUMAN: 5%, REMARKS: SEVERE IRRITATION
EFFECT. CHRONIC EXPOSURE CARCINOGEN (SEE EXPLANATION OF
CARCINOGENICITY - ): RAT - ORAL: 25750 MG/KG 2Y C, R ESULT:
TUMORGENIC: NEOPLASTIC BY RTECS CRITERIA; KIDNEY, URETER, BLADDER:
KIDNEY TUMORS. (CONTACT NA VY ENVIRONMENTAL HEALTH CENTER FOR
ADDITIONAL INFORMATION)